Dk Bio Inc.

Rejuran is a series of skin boosters based on salmon-derived polynucleotide (PDRN). PDRN promotes regeneration of all epidermis/dermis layers by stimulating the production of collagen, elastin, and contributing to restoration of the extracellular matrix. Rejuran products are FDA-approved and EC-certified; they are aimed at long-term skin rejuvenation and hydration.   Strengths of Rejuran: ·         faster tissue regeneration and wound/scar healing compared to other products containing HA only as an active component ·         clinically proven increase in the skin’s thickness ·         2-fold enhanced skin elasticity compared to other products based on HA only ·         long-lasting effect ·         volumization effect due to the 3-D polymeric structure ·         minimum restoration time after the procedure ·         highly biocompatible composition guarantees the absence of adverse reactions   Rejuran is a dermal booster for promoting collagen secretion and skin rejuvenation. Rejuran is aimed at correcting a wide spectrum of folds and wrinkles, fighting undesired skin pigmentation, and improving the skin’s thickness and hydration rate.   Scope of Rejuran: ·         treatment of dark skin discoloration (melisma, rosacea) ·         pore narrowing ·         wrinkle filling ·         treatment of atrophic (including acne) scars ·         correction of the gravitational ptosis ·         moisturization of the dry and dehydrated skin   The esthetic effect lasts from 6 to 12 months. Product composition: PN, 2% 2 syringes × 2.0 ml per pack

Rejuran is a series of skin boosters based on salmon-derived polynucleotide (PDRN). PDRN promotes regeneration of all epidermis/dermis layers by stimulating the production of collagen, elastin, and contributing to restoration of the extracellular matrix. Rejuran products are FDA-approved and EC-certified; they are aimed at long-term skin rejuvenation and hydration.   Strengths of Rejuran: ·         faster tissue regeneration and wound/scar healing compared to other products containing HA only as an active component ·         clinically proven increase in the skin’s thickness ·         2-fold enhanced skin elasticity compared to other products based on HA only ·         long-lasting effect ·         volumization effect due to the 3-D polymeric structure ·         minimum restoration time after the procedure ·         highly biocompatible composition guarantees the absence of adverse reactions   Rejuran is a dermal booster for promoting collagen secretion and skin rejuvenation. Rejuran is aimed at correcting a wide spectrum of folds and wrinkles, fighting undesired skin pigmentation, and improving the skin’s thickness and hydration rate.   Scope of Rejuran: ·         treatment of dark skin discoloration (melisma, rosacea) ·         pore narrowing ·         wrinkle filling ·         treatment of atrophic (including acne) scars ·         correction of the gravitational ptosis ·         moisturization of the dry and dehydrated skin   The esthetic effect lasts from 6 to 12 months. Product composition: PN, 2% 2 syringes × 2.0 ml per pack Needle size: 33G, 4 mm

Rejuran is a series of skin boosters based on polydeoxyribonucleotide (PDRN). Rejuran products are aimed at effective and fast rejuvenation and hydration of the superficial and deep skin layers.   Strengths of Rejuran: ·         the product is FDA-approved, and CE-certified ·         immediate and long-lasting skin hydrating effect ·         clinically proven increase in the skin’s thickness and brightness ·         2-fold enhanced skin elasticity as compared to other products based on HA only   Rejuran HB is a skin booster for dermal repair and hydration. Rejuran HB stimulates the production of collagen and elastin, triggers proliferation of fibroblasts: it literally repairs the skin. The booster can be injected into various parts of the face and neck, décolleté, elbows, knees, as well as back sides of the hand. The presence of lidocaine in the composition reduces painful sensations during the injection procedure.   Scope of Rejuran HB: ·         treatment of early signs of aging (fine and superficial wrinkles) ·         damaged skin repair (due to UV exposure and excessive cosmetic treatment) ·         skin texture and tone improvement ·         smoothing acne scars ·         prolonged skin hydration The esthetic effect lasts from 6 to 12 months. Product composition: PN, 1%, HA, 1%, lidocaine, 0.3% 1 syringe × 1.0 ml per pack Needle size: 33G

Rejuran is a series of skin boosters based on salmon-derived polynucleotide (PDRN). Strengths of Rejuran: ·         the product is FDA-approved, and CE-certified ·         faster tissue regeneration and wound/scar healing compared to other products containing HA only as an active component ·         clinically proven increase in the skin’s thickness ·         2-fold enhanced skin elasticity as compared to other products based on HA only ·         long-lasting esthetic effect   Rejuran S has been developed specifically for reducing the appearance of acne scarring. Polynucleotide, the active component in Rejuran S, promotes collagen and elastin production thus providing a direct skin-healing effect.   Scope of Rejuran S: ·         healing of deep acne scars, wounds, and other skin imperfections ·         evening of the skin texture   The esthetic effect lasts from 6 to 12 months. Product composition: PN, 1% 1 syringe × 1.0 ml per pack Needle size: 34G   Rejuran I is a skin booster developed specifically for delicate under and around eye area. Rejuran I also improves skin elasticity and evens its tone and texture.   Scope of Rejuran I: reduction of dark under-eye circles and swelling (under-eye bags) treatment of early signs of aging in the periorbital area (crow’s feet, fine under-eye lines) restoration of thinned skin after cosmetic procedures moisturization of dry and dehydrated skin   The esthetic effect lasts from 6 to 12 months. Product composition: PN, 1% 1 syringe × 1.0 ml per pack Needle size: 34G, 4mm

Celosome presents a series of 100% cross-linked hyaluronic acid (HA) fillers. Celosome Aqua is used for biorevitalizaton. The filler is injected into the superficial dermis.   Scope of Celosome Aqua: ·         deep skin hydration ·         treatment of early signs of aging (superficial-to-mid wrinkles, saggy skin) ·         evening of the skin tone ·         brightening of dull skin   The aesthetic effect lasts from 1 to 3 months. Product composition: HA, 24 mg/ml, Mannitol, 0.9% 5 syringes × 2.5 ml per pack   Celosome Aqua Lido HA, 24 mg/ml, Mannitol, 0.9% 5 syringes × 2.5 ml per pack Lidocaine 1.5mg/ml

Rejeunesse Sparkle is a low density dermal filler for skin rejuvenation. Rejeuness Benefits: hyaluronic acid of non-animal origin of high purity. · no residual BDDE. prolonged effect. painless procedure. Application area: biorevitalization; prevention and elimination of fine wrinkles; lip augmentation; vector lifting; bioreinforcement; The duration of the effect is from 6 to 8 months. Composition: 20 mg/ml, Lidocaine 0.3%. 3 x 2.5 ml syringes per pack.

DEMEI PIus Cream (GMP Approved) Lidocaine 25mg / Prilocaine 25mg [Ingredients and Quantity] Out of 1g Active Ingredient : Lidocaine(KP) 25.0mg / Prilocaine(BP) 25.0mg Additive (Preservatice) : Methyl Paraoxybenzoate(KP) 1.0mg Oher Additives : Glycerin Monastearate, N-Methylpyrrolidone, Liquid Paraffin, Isopropyl Myristate, Purified Water, Carbomer 940, Polysorbate 60, Propylene Glycol [Appearance] White Cream [Indication] 1. Surface anesthesia of the skin during needle insertion or surgical procedures 2. Anesthesia of the genital mucosa (e.g., prior to removal of condyloma) 3. Surface anesthesia of leg ulcers prior to irrigation or topical surgery (e.g., removal of fibrin, pus, or subcutaneous tissue) [Application Precautions] Do not apply this medicine around the eyes as it may cause corneal irritation. If this medicine comes into contact with the eyes, the eyes should be flushed with water or sodium chloride solution and should be protected until numbness returns. As with other local anesthetics, this drug may be toxic to the ear and should not be applied to the middle ear, and this drug should not be used for procedures or paracentesis that may penetrate the middle ear. It does not apply to open erosions. [Treatment in case of overdose] Clinically significant methemoglobinemia in children has been rarely reported High doses of prilocaine may increase methemoglobin. In 3-month-old infants, 125 mg of prilocaine, when applied topically for 5 hours, resulted in moderate methemoglobinemia. Lidocaine at 8.6 to 172 mg/kg caused severe poisoning in infants. [Package] 450g/Jar [Storage] Store in airtight container at room temperature (1-30 ℃) [Shelf Life] 36 months from date of manufacture

DEMEI Caine Cream (GMP Approved) Lidocaine 10.56 % [Ingredients and Quantity] Out of 1g Active Ingredient : Lidocaine(KP) 10.56mg Additive (Preservatice) : Methyl Paraoxybenzoate(KP) 1.0mg Other Additives : Stearyl alcohol, isopropyl myristate, purified water, carbomer 940, trolamine, polysorbate 60, ethanol [Appearance] Whitish yellow cream [Indication] Local anesthesia of the application site [Dosage & Administration] Apply 0.25-0.66g (23-62mg as lidocaine) to the application site 5 to 15minutes prior to the procedure for adults. Do not exceed 2g (184mg as lidocaine) in 24 hours. [Usage Precaution] 1, Do not administer to following patients  1) Patients with hypersensitivity to this drug or other amide local anesthetics.  2) Do not apply over wounds or infected skin.  3) Do not use on pregnant patient. 2. Be careful administering to following patients  1) patients with kidney or liver disease. 3. General Precautions  1) Stop use and consult with your doctor if patient shows sign of rash or imitation.  2) Do not exceed three months of application without the supervision of a doctor. 4. Application  1) For external use only. Avoid application on eyes and nose.  2) Avoid applying multiple layers on the same area. 5. Storage and handling Precautions  1) Keep out of reach of infants and children.  2) Sealed shaded containers. Store in room temperature (1-30 ℃)  3) Do not throw in fire after use. [Package] 450g/Jar [Storage] Store in airtight container at room temperature (1-30 ℃) [Shelf Life] 36 months from date of manufacture

Skin booster based on hyaluronic acid with the addition of PDRN 0.5%. * Recovery * Moisturizing * Wrinkle smoothing * Elasticity * Radiance * Whitening effect HA + Sodium DNA 0.5% 4.0 ml x 5 vials

Shine booster based on hyaluronic acid * Active moisturizing * Adding radiance * Smoothing wrinkles * Whitening effect 4.0ml x 5 vials